Ph.D., University of North Texas, 2001
Synthetic Organic Chemistry
The oxime ether group is beginning to be incorporated into many pharmaceutical and
agricultural compounds. In many cases this group enhances the bioavailability and
effectiveness of the compound. Unfortunately, this oxime ether group can exist in
two geometric configurations and generally only one configuration is acceptable in
the desired product. This necessitates a cumbersome and expensive separation process.
Our research concentrates on developing new synthetic pathways to oxime ethers where the geometric configuration (stereochemistry) of the group is controlled so that only one or predominantly one configuration is formed.
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